L-carnitine
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General Facts

Carnitine is a micronutrient found in meat and dairy
products that translocates long-chain fatty acids into the
cell, where it can be converted into energy

It appears to have neuroprotective properties and it has
recently been shown to reduce attention deficits in
patients with Alzheimer's disease (AD) after long-term
treatment

L-Carnitine is primarily used to treat heart related
problems, and some studies have suggested that
supplemental L-Carnitine in combination with angina may
help symptoms in those suffering from angina.

Carnitine may help reduce death rate after a heart attack.
In a 12-month placebo-controlled study, 160 individuals
who had experienced a heart attack received 4 g of
L-carnitine daily or placebo, in addition to other
conventional medication. The mortality rate in the treated
group was significantly lower than in the placebo group,
1.2% versus 12.5%, respectively.

There were also improvements in heart rate, blood
pressure, angina (chest pain), and blood lipids. A larger
double-blind study of 472 people found that carnitine may
improve the chances of survival if given within 24 hours
after a heart attack. Note: Carnitine is used along with
conventional treatment, not as a substitute for it

L-carnitine helps alleviating thyroid side effects
(A double-blind, placebo-controlled trial found evidence
that use of L-carnitine could alleviate many of these
symptoms. This 6-month study evaluated the effects of
L-carnitine in 50 women who were taking thyroid
hormone for benign goiter. The results showed that a
dose of 2 or 4 g of carnitine daily protected participants'
bones and reduced other symptoms of hyperthyroidism)

Evidence from three double-blind placebo-controlled
studies enrolling a total of 49 individuals suggests that
L-carnitine can improve exercise tolerance in COPD,
presumably by improving muscular efficiency in the lungs
and other muscles

L-carnitine is especially valuable to the proper functioning
of the heart
L-carnitine is made in the body from the amino acids lysine and methionine, and is needed to release energy from fat. It
transports fatty acids into mitochondria, the powerhouses of cells. Dairy and red meat contain the greatest amounts of
carnitine
L-carnitine
L-carnitine, which has already been shown to produce
beneficial effects in the treatment of the chronic phase of
peripheral vascular disease, was also found in this study to
have greater effects in delaying disease progression than
pentoxifylline, a drug that has been extensively tested for
this indication.

L-carnitine, therefore, appears to be a promising treatment
option in patients with PAD and should be further explored
in large randomised, long-term controlled trials.
More scientific.....

Compared with testosterone, carnitines were significantly
more active in improving nocturnal penile tumescence  
and International Index of Erectile Function score.

Testosterone, but not carnitines, significantly increased
the prostate volume and free and total testosterone levels
and significantly lowered serum luteinizing hormone.
Prostate-specific antigen (PSA) and prolactin did not
change significantly in any group.

Carnitines and testosterone were effective for as long as
they were administered, with reversal to baseline values
when treatment was stopped. Six months after
testosterone suspension, prostate volume remained
significantly greater than baseline.
Urology. 2004;63:641-646
Collagen + Aloe Vera + Pyruvate + L-Carnitine + Conjugated linoleic acid (CLA)
Go to pharmacy clinic
A double-blind placebo-controlled trial that enrolled 431
participants for 1 year found no significant improvement at
all in the group treated with acetyl-L-carnitine. A close look
at the results appeared to suggest some benefit in
individuals who developed Alzheimer's disease at a
particularly young age. However, when this possibility was
tested in a 1-year double-blind placebo-controlled trial of
229 patients with early-onset Alzheimer's, no benefits were
seen
Research has shown that supplementing with L-carnitine
as part of an exercise routine can help reduce muscle
soreness.
Most people do not need carnitine supplements. For
therapeutic use, typical amounts are 1 to 3 grams per day.
Dairy and red meat contain the greatest amounts of
carnitine. Therefore, people who have a limited intake of
meat and dairy products tend to have lower L-carnitine
intakes. Carnitine deficiencies are rare, even in strict
vegetarians, because the body produces carnitine
relatively easily
GNC Acetyl-L-Carnitine 500, 500mg, Capsules
GNC Pro Performance L-Carnitine, 500 mg, Tablets
GNC Pro Performance Liquid L-Carnitine Dietary Supplement, Cherry
Nature's Bounty Acetyl L-Carnitine 250mg, Capsules
Nature's Way L-Carnitine 500mg Vegetarian Vcaps
Twinlab Acetyl L-Carnitine, 500mg, Capsule
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